We have several employee which have this problem. Since one week, the users can't save or open documents over the CRM 2011 Plugin for Outlook. They always get the error message "this content cannot be displayed in a frame". But when they do it with the Internet Explorer it is working. So we get this error just over the CRM Plugin.
We have IE 9 installed and using Outlook 2010 with the CRM 2011 Plugin. We also use office365, Microsoft Dynamics CRM Online and sharepoint.